The story begins with the narrator and his friend John Gordon arriving at the estate of Sir Thomas Cameron, a noted but ruthless Egyptologist. They are greeted by Ganra Singh, a noseless Sikh servant, whose unsettling appearance hints at the dark tone of the narrative. As night envelops the estate, the setting grows increasingly sinister, with the wind whispering secrets and the manor casting foreboding shadows.

Inside, Sir Thomas reveals his latest archaeological find—a peculiarly preserved mummy that he believes will revolutionize historical understanding. However, his disregard for ethical boundaries in his professional pursuits hints at past misdeeds, specifically a malevolent act against a rival, Gustave Von Honmann, which led to the latter's death. The tension in the narrative builds as Sir Thomas's callous nature and controversial reputation are juxtaposed against his significant scientific contributions.

As the evening progresses, a scream pierces the night, leading the narrator and Gordon to discover Sir Thomas fatally wounded, uttering delirious exclamations about "the noseless one" before succumbing to his injuries. The initial suspicion falls on Ganra Singh, who is temporarily confined.

The plot thickens with the disappearance of the celebrated mummy, suggesting a connection between it and the ongoing mysterious events. The narrator experiences a surreal encounter, sensing a supernatural presence linked to the missing mummy, which embodies an inexplicable and ancient malevolence.

The climax is a dramatic confrontation where the reanimated mummy attacks, only to be thwarted by Ganra Singh, who reveals his loyalty and bravery. The mummy, driven by the spirit of Von Honmann seeking revenge, is ultimately destroyed in a fire, its malevolent existence extinguished by the purifying flames.

In the denouement, the characters reflect on the possibility that the mummy was animated by the spirit of Von Honmann, bridging the gap between life and death through sheer malevolent will, raising philosophical questions about the nature of existence and the potentially thin veils separating the living from spectral realms.